PI720203

DARPP-32 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI720203-Each-of-1 In Stock ₹ 48,371.50

PI720203 - Each of 1

₹ 48,371.50

In Stock

Quantity

1

Base Price: ₹ 48,371.50

GST (18%): ₹ 8,706.87

Total Price: ₹ 57,078.37

Antigen

DARPP-32

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ppp1r1b

Gene Alias

AU040756; DARPP32; DARPP-32; dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine and cAMP-regulated neuronal phosphoprotein 32; dopamine- and cAMP-regulated phosphoprotein DARPP-32; FLJ20940; IPPD; neuronal phosphoprotein DARPP-32; OTTHUMP00000164275; OTTHUMP00000164276; Ppp1r1b; PPR1B; protein pho; protein phosphatase 1 regulatory inhibitor subunit 1B; protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1, regulatory (inhibitor) subunit 1B

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19049, 360616, 84152

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

Q60829, Q6J4I0, Q9UD71

Gene Symbols

Ppp1r1b

Immunogen

Protein corresponding to Human PPP1R1B (aa 1-204)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
  • The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
  • The purified antibody is tested for its functionality in various relevant research applications
  • The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
  • This antibody is predicted to react with Monkey, Pig, Horse and Cat DARPP-32 is a dopamine (DA) and AMP-regugated ∽32 kDa phosphoprotein that is associated with dopaminoceptive neurons
  • The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34
  • In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA
  • Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission
  • In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac®.