PI720357

mGluR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI720357-Each-of-1 In Stock ₹ 49,439.50

PI720357 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

mGluR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRM2

Gene Alias

4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; GLUR2; glutamate metabotropic receptor 2; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; GPRC1B; Grm2; M mGlu2; Metabotropic; Metabotropic glutamate receptor 2; mGlu2; MGLUR2; mGluR7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2912

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q14416

Gene Symbols

GRM2

Immunogen

Peptide corresponding to Human GRM2 (aa 429-444)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
  • The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
  • The purified antibody is tested for its functionality in various relevant research applications
  • The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
  • This antibody is predicted to react with Monkey, Rabbit and Bovine
  • Glutamate is the main excitatory neurotransmitter in the brain
  • For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission
  • Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins
  • These receptors are called metabotropic glutamate receptors
  • In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores
  • Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase
  • The Group-I receptors include mGluR1a and mGluR5
  • The Group-II receptors in include mGluR2 and mGluR3.