PIMA122669
Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA122669-Each-of-1 | In Stock | ₹ 50,507.50 |
PIMA122669 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,507.50
GST (18%): ₹ 9,091.35
Total Price: ₹ 59,598.85
Antigen
Bacillus anthracis Lethal Factor
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Target Species
Bacteria
Product Type
Antibody
Isotype
IgG1
Applications
ELISA
Clone
BAL0106
Conjugate
Unconjugated
Gene Alias
Anthrax LF; B. anthracis LF
Immunogen
Highly purified lethal factor antigen of Bacillus anthracis.
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- MA1-22669 detects Bacillus anthracis lethal factor in Bacteria samples
- Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium Bacillus anthracis, the causative agent of anthrax
- Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF)
- These three protein components act together to impart their physiological effects
- Assembled complexes containing the toxin components are endocytosed
- In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell
- Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration
- The toxin may even induce cell lysis, as is observed for macrophage cells
- Anthrax toxin allows the bacteria to evade the immune system, proliferate, and μgtimately kill the host animal
- Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.