PIMA123347

FANCD2 Monoclonal Antibody (6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA123347-Each-of-1 In Stock ₹ 47,036.50

PIMA123347 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

FANCD2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

Q9BXW9

Gene Symbols

FANCD2

Immunogen

Human FANCD2 fusion protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

6

Conjugate

Unconjugated

Gene

FANCD2

Gene Alias

2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

2177

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-23347 detects FANCD2 in Human samples
  • FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability
  • It promotes accurate and efficient pairing of homologs during meiosis
  • FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing
  • It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress
  • FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin
  • Defects in the FANCD2 gene result in Fanconi anemia complementation group D2
  • This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.