FANCD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120776-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120776 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
FANCD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FANCD2
Gene Alias
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2177, 312641
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
1.1 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
Q6IV68, Q9BXW9
Gene Symbols
FANCD2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of FANCD2 (NP_001018125.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: MCF7, HeLa, K-562, Jurkat, A-549
- The target is usually found in the following locations: Nucleus
- Immunogen sequence: AFSKQNEASS HIQDDMHLVI RKQLSSTVFK YKLIGIIGAV TMAGIMAADR SESPSLTQER ANLSDEQCTQ VTSLLQLVHS CSEQSPQASA LYYDEFANLI QHEKLDPKAL EWVGHTICND FQDAFVVDSC VVPEGDFPFP VKALYGLEEY DTQDGIAINL LPLLFSQDFA KDGGPVTSQE S FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability
- It promotes accurate and efficient pairing of homologs during meiosis
- FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing
- It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress
- FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin
- Defects in the FANCD2 gene result in Fanconi anemia complementation group D2
- This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.