PIMA134142

CD7 Monoclonal Antibody (LT7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA134142-Each-of-1 In Stock ₹ 67,951.50

PIMA134142 - Each of 1

₹ 67,951.50

In Stock

Quantity

1

Base Price: ₹ 67,951.50

GST (18%): ₹ 12,231.27

Total Price: ₹ 80,182.77

Antigen

CD7

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P09564

Gene Symbols

CD7

Immunogen

Normal human peripheral blood lymphocytes

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

LT7

Conjugate

Unconjugated

Gene

CD7

Gene Alias

Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

924

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily
  • CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects
  • CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia
  • Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells
  • Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation
  • CD7 associates directly with phosphoinositol 3'-kinase
  • CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation
  • Expression of CD7 is an important marker used in leukemia diagnostics.