E-selectin Monoclonal Antibody (CL2/6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA134486-Each-of-1 | In Stock | ₹ 62,389.00 |
PIMA134486 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 62,389.00
GST (18%): ₹ 11,230.02
Total Price: ₹ 73,619.02
Antigen
E-selectin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P16581
Gene Symbols
SELE
Immunogen
Proprietary immunogen - Contact ABR for details.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone
CL2/6
Conjugate
Unconjugated
Gene
SELE
Gene Alias
CD62 antigen-like family member E; CD62E; e selectin; Elam; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule; endothelial leukocyte adhesion molecule 1; endothelial leukocyte adhesion molecule I; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin, endothelial cell
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
6401
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes
- In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation
- This response is immediate and involves a cascade of adhesion receptors
- At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade
- Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium
- E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines
- In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade
- E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.