CD62E/CD62P Monoclonal Antibody (1.2B6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA180430-Each-of-1 | In Stock | ₹ 59,185.00 |
PIMA180430 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,185.00
GST (18%): ₹ 10,653.30
Total Price: ₹ 69,838.30
Antigen
CD62E/CD62P
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P16109, P16581, P98110
Gene Symbols
SELE, SELP
Immunogen
Human E-Selectin (ELAM-1).
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human, Porcine
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
1.2B6
Conjugate
Unconjugated
Gene
SELP
Gene Alias
CD62; CD62 antigen-like family member E; CD62 antigen-like family member P; CD62E; CD62P; CD62P; CD62 homolog; ELAM; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule 1; ESEL; E-selectin; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; GRMP; LECAM2; LECAM-2; LECAM3; LECAM-3; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; P-selectin; P-selectin precursor; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); SELP
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
397150, 397508, 6401, 6403
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA1-80430 inhibits neutrophil adhesion to E-selectin and to P-selectin
- Non-reducing conditions are recommended for Western blot applications
- A suggested positive control is human tonsil
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Mouse anti Human CD62E/CD62P antibody, clone 1.2B6 recognizes the human CD62E and CD62P cell surface antigens
- CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1)
- It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes
- Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140
- It is expressed on platelets, megakaryocytes, and epithelium
- It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis
- The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.