Protein C Monoclonal Antibody (5071), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA143015-Each-of-1 | In Stock | ₹ 29,414.50 |
PIMA143015 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,414.50
GST (18%): ₹ 5,294.61
Total Price: ₹ 34,709.11
Antigen
Protein C
Classification
Monoclonal
Concentration
7.0 mg/mL
Formulation
50% water with 50% glycerol and no preservative
Gene Accession No.
P04070
Gene Symbols
PROC
Immunogen
Human activated protein C.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Radioimmune Assays (RIA), Western Blot
Clone
5071
Conjugate
Unconjugated
Gene
PROC
Gene Alias
Activation peptide; Anticoagulant protein C; APC; autoprothrombin IIA; Blood coagulation factor XIV; EDQVDPRLIDGK; inactivator of coagulation factors Va, VIII; PC; prepro-protein C; Proc; PROC1; protein C; protein C (inactivator of coagulation factors Va and VIIIa); protein C prepropeptide; protein C, inactivator of coagulation factors Va and VIIIa; THPH3; THPH4; type I protein C; vitamin K-dependent protein C; Vitamin K-dependent protein C heavy chain; Vitamin K-dependent protein C light chain
Host Species
Mouse
Purification Method
Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5624
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-43015 detects Protein C in human samples
- MA1-43015 has successfully been used in RIA and Western blot applications
- MA1-43015 was derived from human protein C and activated protein C
- Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex
- Protein C in its activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII
- Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains
- The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation
- The molecular weight of the active enzyme is 55 kDa and the normal concentrations in human plasma is approximately 1-3 ng/mL because of the very fast turnover, the proenzyme concentration is approximately 3 μg/mL
- Mutations in the Protein C gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.