Protein C Monoclonal Antibody (5072), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA143016-Each-of-1 | In Stock | ₹ 29,414.50 |
PIMA143016 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,414.50
GST (18%): ₹ 5,294.61
Total Price: ₹ 34,709.11
Antigen
Protein C
Classification
Monoclonal
Concentration
4.9 mg/mL
Formulation
50% water with 50% glycerol and no preservative
Gene Accession No.
P04070
Gene Symbols
PROC
Immunogen
Human protein C
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA
Clone
5072
Conjugate
Unconjugated
Gene
PROC
Gene Alias
Activation peptide; Anticoagulant protein C; APC; autoprothrombin IIA; Blood coagulation factor XIV; EDQVDPRLIDGK; inactivator of coagulation factors Va, VIII; PC; prepro-protein C; Proc; PROC1; protein C; protein C (inactivator of coagulation factors Va and VIIIa); protein C prepropeptide; protein C, inactivator of coagulation factors Va and VIIIa; THPH3; THPH4; type I protein C; vitamin K-dependent protein C; Vitamin K-dependent protein C heavy chain; Vitamin K-dependent protein C light chain
Host Species
Mouse
Purification Method
Ammonium sulfate precipitation, Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5624
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-43016 detects Protein C in human samples
- MA1-43016 has successfully been used in ELISA applications
- MA1-43016 was derived from human protein C
- Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex
- Protein C in its activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII
- Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains
- The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation
- The molecular weight of the active enzyme is 55 kDa and the normal concentrations in human plasma is approximately 1-3 ng/mL because of the very fast turnover, the proenzyme concentration is approximately 3 μg/mL
- Mutations in the Protein C gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.