PIMA170066

I-Ek Monoclonal Antibody (14-4-4S), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA170066-Each-of-1 In Stock ₹ 41,385.00

PIMA170066 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

I-Ek

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P04230, P14439

Gene Symbols

H2-Ea-ps, H2-Eb1

Immunogen

C3H.

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

14-4-4S

Conjugate

Unconjugated

Gene

H2-Eb1

Gene Alias

AI323765; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia3; Ia-3; Ia4; Ia-4; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; major histocompatibility complex H-2E beta chain; MGC117888; MHC class II antigen E alpha; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100504404, 14969

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-70066 detects I-Ek in mouse samples
  • MA1-70066 has been successfully used in flow cytometry and cytotoxicity studies
  • The MA1-70066 immunogen is C3H
  • MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells
  • Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells
  • The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.