ICAM-1 Monoclonal Antibody (84H10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA180611-Each-of-1 | In Stock | ₹ 59,897.00 |
PIMA180611 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,897.00
GST (18%): ₹ 10,781.46
Total Price: ₹ 70,678.46
Antigen
ICAM-1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with <0.1% sodium azide; pH 7.4
Gene Accession No.
P05362, P33729
Gene Symbols
ICAM1
Immunogen
K562 cell line.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
84H10
Conjugate
Unconjugated
Gene
ICAM1
Gene Alias
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3383, 403975
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product contains sodium azide; removal by dialysis is recommended prior to use in functional assays
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Mouse anti Human CD54 antibody, clone 84H10 recognizes the D1 domain of ICAM-1
- ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain
- ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102)
- ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor
- ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation
- ICAM-1 is also detected in some carcinoma and melanoma cells
- Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.