ICAM-1 Monoclonal Antibody (15.2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511569-Each-of-1 | In Stock | ₹ 52,376.50 |
PIMA511569 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,376.50
GST (18%): ₹ 9,427.77
Total Price: ₹ 61,804.27
Antigen
ICAM-1
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P05362
Gene Symbols
ICAM1
Immunogen
Human monocytes
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunohistochemistry (Frozen)
Clone
15.2
Conjugate
Unconjugated
Gene
ICAM1
Gene Alias
BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3383
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-11569 targets CD54 in FACS and IHC (F) applications and shows reactivity with Human samples
- The MA5-11569 immunogen is human monocytes
- ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain
- ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102)
- ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor
- ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation
- ICAM-1 is also detected in some carcinoma and melanoma cells
- Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.