CD46 Monoclonal Antibody (MEM-258), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA182140-Each-of-1 | In Stock | ₹ 53,756.00 |
PIMA182140 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,756.00
GST (18%): ₹ 9,676.08
Total Price: ₹ 63,432.08
Antigen
CD46
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P15529
Gene Symbols
CD46
Immunogen
HPB-ALL cell line.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
MEM-258
Conjugate
Unconjugated
Gene
CD46
Gene Alias
AHUS2; antigen identified by monoclonal antibody TRA-2-10; brain microvascular membrane cofactor; brain microvascular membrane cofactor protein CD46; Cd46; CD46 antigen, complement regulatory protein; CD46 complement regulatory protein; CD46 molecule; CD46 molecule, complement regulatory protein; CD46 splice variant; complement membrane cofactor protein; complement regulatory protein; Mcp; MCP; complement activation regulator; measles virus receptor; membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); membrane cofactor protein variant 10; membrane cofactor protein variant 7; membrane cofactor protein variant 8; membrane cofactor protein variant 9; MGC26544; MIC10; soluble membrane cofactor protein variant 11; soluble membrane cofactor protein variant 12; soluble membrane cofactor protein variant 13; TLX; TRA2.10; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4179
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product contains sodium azide; removal by dialysis is recommended prior to use in functional assays
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Mouse anti Human CD46 antibody, clone MEM-258 recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP)
- CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction
- CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function
- CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.