PIMA182715

CD68 Monoclonal Antibody (Ki-M7), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA182715-Each-of-1 In Stock ₹ 49,973.50

PIMA182715 - Each of 1

₹ 49,973.50

In Stock

Quantity

1

Base Price: ₹ 49,973.50

GST (18%): ₹ 8,995.23

Total Price: ₹ 58,968.73

Antigen

CD68

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

PBS with 1% BSA and 0.05% sodium azide

Gene Accession No.

P34810

Gene Symbols

Cd68

Immunogen

Cell suspensions of human lymph node.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry

Clone

Ki-M7

Conjugate

FITC

Gene

Cd68

Gene Alias

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

968

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • Membrane permeabilization is required for flow cytometry applications
  • For FACS analysis, use 20 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Mouse anti Human CD68 antibody, clone Ki-M7 recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of macrophages/monocytes, including Kupffer cells, microglia, histiocytes and osteoclasts, and is expressed to a lesser extent by dendritic cells and peripheral blood granulocytes
  • CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes
  • Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions
  • CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma
  • Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.