PIMA324A647
P-cadherin Monoclonal Antibody (12H6), Alexa Fluor™ 647, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA324A647-Each-of-1 | In Stock | ₹ 41,741.00 |
PIMA324A647 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,741.00
GST (18%): ₹ 7,513.38
Total Price: ₹ 49,254.38
Antigen
P-cadherin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.
P22223
Gene Symbols
Cdh3
Immunogen
Human P-Cadherin fusion protein
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry
Clone
12H6
Conjugate
Alexa Fluor 647
Gene
Cdh3
Gene Alias
AI385538; CADH3; cadherin 15, M-cadherin (myotubule); cadherin 3; cadherin 3, type 1, P-cadherin (placental); cadherin-3; Cadp; calcium-dependent adhesion protein, placental; CDH3; CDHP; HJMD; PCAD; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1001
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily
- Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin
- Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation
- P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium
- P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle
- Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas
- Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.