PRDM2 Monoclonal Antibody (33AT1045), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511144-Each-of-1 | In Stock | ₹ 49,884.50 |
PIMA511144 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
PRDM2
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q13029
Gene Symbols
PRDM2
Immunogen
Purified recombinant GST fusion protein encoding aa 1-347 of RIZ1.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
ChIP Assay, Western Blot
Clone
33AT1045
Conjugate
Unconjugated
Gene
PRDM2
Gene Alias
4833427P12Rik; E330024L24Rik; G3b; GATA-3 binding protein G3B; GATA-3-binding protein G3B; Gm1033; Gm19732; HUMHOXY1; KMT8; lysine N-methyltransferase 8; MTBzf; MTB-ZF; MTE-binding protein; PR domain 2; PR domain containing 2, with ZNF domain; PR domain zinc finger protein 2; PR domain-containing protein 2; Prdm2; retinoblastoma interacting zinc finger protein; retinoblastoma protein-binding zinc finger protein; retinoblastoma protein-interacting zinc finger protein; RIZ; RIZ1; RIZ2; RP5-1177E19.1; zinc finger protein RIZ; zinc-finger DNA-binding protein; Znfpr1c1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
110593, 7799
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2)
- PRDM2, a member of nuclear/histone methyltransferase superfamily, consists of an N-terminal PR domain, an Rb-binding motif, 8 Kruppel-like zinc finger motifs, Nuclear hormone-receptor binding motif and a C-terminal PR-domain binding motif
- Ubiquitously expressed in low levels, PRDM2 exists in 2 isoforms, a 280 kDa RIZ1 containing PR-domain and a 250 kDa truncated RIZ2 that lacks PR-domain
- A tumor suppressor with a prominent role in cell growth and differentiation, PRDM2 binds to Retinoblastoma protein, estrogen receptor, GATA-3 and TPA-responsive element (MTE) of Heme-oxygenase-1 gene and influences pathogenesis of Retinoblastoma, transcriptional regulation during neuronal differentiation, transactivation of Heme-oxygenase-1 gene and specific effector of estrogen action
- It is inactivated or altered due to mutations and hypermethylation in many types of human cancers suggesting a potential biomarker.