HACE1 Monoclonal Antibody (8D3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517701-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA517701 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
HACE1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q8IYU2
Gene Symbols
HACE1
Immunogen
Mouse monoclonal antibodies raised against His-tagged recombinant full length Human HACE1.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone
8D3
Conjugate
Unconjugated
Gene
HACE1
Gene Alias
1700042J16Rik; A730034A22Rik; BC025474; E3 ubiquitin-protein ligase HACE1; hace 1; Hace1; HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1; HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1; HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1; HECT-type E3 ubiquitin transferase HACE1; KIAA1320; SPPRS
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
57531
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17701 targets Hace 1 in ELISA, IF, IHC (P), and WB applications and shows reactivity with Human samples
- The MA5-17701 immunogen is mouse monoclonal antibodies raised against His-tagged recombinant full length Human HACE1
- E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases
- Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion
- Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division
- Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens
- May also act as a transcription regulator via its interaction with RARB.