PCAF Monoclonal Antibody (E.107.0), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511186-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA511186 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
PCAF
Classification
Monoclonal
Concentration
358 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
Q92831, Q9JHD1
Gene Symbols
KAT2B
Immunogen
Synthetic peptide corresponding to the amino terminus of human PCAF protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Immunoprecipitation, Western Blot
Clone
E.107.0
Conjugate
Unconjugated
Gene
KAT2B
Gene Alias
A930006P13Rik; AI461839; AW536563; CAF; CREBBP-associated factor; histone acetylase PCAF; Histone acetyltransferase KAT2B; histone acetyltransferase PCAF; K(lysine) acetyltransferase 2B; Kat2b; Lysine acetyltransferase 2B; P/ PCAF; P/CAF; P300/CBP-associated factor; Pcaf; Spermidine acetyltransferase KAT2B
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18519, 301164, 8850
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with the related GCN5L2 protein
- PCAF (histone acetyltransferase KAT2B) functions as a histone acetyltransferase (HAT) to promote transcriptional activation
- It has significant histone acetyltransferase activity with core histones (H3 and H4) and nucleosome core particles
- PCAF also acetylates non-histone proteins such as ACLY, PLK4, and TBX5
- It inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A
- PCAF also acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers
- It is involved in heart and limb development by mediating acetylation of TBX5 and acetylation regulating nucleocytoplasmic shutting of TBX5.