PIMA511620

Calponin 1 Monoclonal Antibody (CALP), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA511620-Each-of-1 In Stock ₹ 53,311.00

PIMA511620 - Each of 1

₹ 53,311.00

In Stock

Quantity

1

Base Price: ₹ 53,311.00

GST (18%): ₹ 9,595.98

Total Price: ₹ 62,906.98

Antigen

Calponin 1

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P51911, Q08091, Q08290

Gene Symbols

CNN1

Immunogen

Crude human uterus extract

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

CALP

Conjugate

Unconjugated

Gene

CNN1

Gene Alias

Basic calponin; calponin; calponin 1; calponin 1, basic, smooth muscle; calponin 1, smooth muscle; calponin H1, smooth muscle; Calponin-1; calponins, basic; CN; CNN1; CnnI; epididymis secretory protein Li 14; h1-calponin; HEL-S-14; similar to calponin 1, basic, smooth muscle; Sm-Calp; SMCC; smooth muscle calponin h1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1264, 12797, 65204

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-11620 targets Calponin-1 in IHC (P) applications and shows reactivity with Human and Rat samples
  • The MA5-11620 immunogen is crude human uterus extract
  • Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction
  • It is capable of binding to actin, calmodulin, troponin C and tropomyosin
  • Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle
  • Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa
  • Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract
  • The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions
  • It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers
  • It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma
  • Adenoid cystic carcinoma in salivary gland tumors is calponin positive.