PIMA191860

alpha Actinin 1 Monoclonal Antibody (0.T.02), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA191860-Each-of-1 In Stock ₹ 55,625.00

PIMA191860 - Each of 1

₹ 55,625.00

In Stock

Quantity

1

Base Price: ₹ 55,625.00

GST (18%): ₹ 10,012.50

Total Price: ₹ 65,637.50

Antigen

alpha Actinin 1

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P12814, Q7TPR4, Q9Z1P2

Gene Symbols

ACTN1

Immunogen

Human alpha Actinin.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone

0.T.02

Conjugate

Unconjugated

Gene

ACTN1

Gene Alias

3110023F10Rik; actinin; actinin 1 smooth muscle; actinin alpha 1; actinin, alpha 1; Actn1; Actn1a; alpha actinin 1a; alpha-actinin; alpha-actinin cytoskeletal isoform; Alpha-actinin-1; BDPLT15; F-actin cross-linking protein; fibroblast alpha actinin; FLJ40884; FLJ54432; hypothetical protein; hypothetical protein LOC524770; I79_004057; non-muscle alpha-actinin 1; non-muscle alpha-actinin-1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

109711, 81634, 87

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recommended positive controls: RIPA lysates from human A431 cells (GTX82919)
  • Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins
  • Alpha actinin is an actin-binding protein with multiple roles in different cell types
  • In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane
  • In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments
  • This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene
  • Three transcript variants encoding different isoforms have been found for this gene.