NOTCH1 Monoclonal Antibody (A6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511961-Each-of-1 | In Stock | ₹ 48,015.50 |
PIMA511961 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,015.50
GST (18%): ₹ 8,642.79
Total Price: ₹ 56,658.29
Antigen
NOTCH1
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P46531, Q01705
Gene Symbols
Notch1
Immunogen
Recombinant protein encoding the ligand binding region of human Notch-1
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
A6
Conjugate
Unconjugated
Gene
Notch1
Gene Alias
9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18128, 4851
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-11961 targets Notch-1 in WB, FACS and ICC/IF applications and shows reactivity with Human and mouse samples
- The MA5-11961 immunogen is recombinant protein encoding the ligand binding region of human Notch-1
- The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region
- Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures
- The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1
- Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).