PIMA512717
Cyclin D3 Monoclonal Antibody (DCS-22), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA512717-Each-of-1 | In Stock | ₹ 52,955.00 |
PIMA512717 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,955.00
GST (18%): ₹ 9,531.90
Total Price: ₹ 62,486.90
Antigen
Cyclin D3
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P30281, P30282, P48961
Gene Symbols
CCND3
Immunogen
Purified human recombinant full length cyclin D3 protein
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
DCS-22
Conjugate
Unconjugated
Gene
CCND3
Gene Alias
9230106B05Rik; AA682053; AL024085; AW146355; C78795; CCND 3; Ccnd3; CGD3; cyclin D3; CyclinD3; Cyl-3; D3 type cyclin; D3-type cyclin; G1/S-specific cyclin-D3; OTTHUMP00000223415; RP5-973N23.3
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
12445, 25193, 896
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-12717 targets Cyclin D3 in FACS, IF, IHC (P), IP, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples
- The MA5-12717 immunogen is purified human recombinant full length cyclin D3 protein
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle
- Cyclins function as regulators of CDK kinases
- Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
- This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition
- This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb
- The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation
- Several transcript variants encoding different isoforms have been found for this gene
- Diseases associated with CCND3 include Retinoblastoma and Plasma Cell Leukemia.