CD137 Monoclonal Antibody (BBK-2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA513739-Each-of-1 | In Stock | ₹ 47,659.50 |
PIMA513739 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,659.50
GST (18%): ₹ 8,578.71
Total Price: ₹ 56,238.21
Antigen
CD137
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q07011
Gene Symbols
TNFRSF9
Immunogen
Ectodomain of human 4-1BB recombinant protein
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Paraffin)
Clone
BBK-2
Conjugate
Unconjugated
Gene
TNFRSF9
Gene Alias
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3604
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-13739 targets CD137 in FACS and IF applications and shows reactivity with Human samples
- The MA5-13739 immunogen is ectodomain of human 4-1BB recombinant protein
- CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells
- Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells
- CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development
- Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival
- Soluble forms of CD137 may provide negative control mechanism for some immune responses.