ERCC1 Monoclonal Antibody (3H11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA513830-Each-of-1 | In Stock | ₹ 52,465.50 |
PIMA513830 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,465.50
GST (18%): ₹ 9,443.79
Total Price: ₹ 61,909.29
Antigen
ERCC1
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P07992
Gene Symbols
ERCC1
Immunogen
Full length recombinant human ERCC1 protein
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
Immunoprecipitation, Western Blot
Clone
3H11
Conjugate
Unconjugated
Gene
ERCC1
Gene Alias
COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2067
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-13830 targets ERCC1 in IP and WB applications and shows reactivity with Human samples
- The MA5-13830 immunogen is full length recombinant human ERCC1 protein
- ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair
- It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL)
- It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure
- ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4
- (Uniprot)