CD1a Monoclonal Antibody (MTB1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514096-Each-of-1 | In Stock | ₹ 49,884.50 |
PIMA514096 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
CD1a
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.
P06126
Gene Symbols
CD1A
Immunogen
Full external domain of CD1a
Regulatory Status
RUO
Gene ID (Entrez)
909
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Clone
MTB1
Conjugate
Unconjugated
Gene
CD1A
Gene Alias
CD1; CD1 antigen; CD1.1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cd1a1; CD1A1 antigen; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a
Host Species
Mouse
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- MA5-14096 targets CD1a in IHC (P) applications and shows reactivity with Human samples
- The MA5-14096 immunogen is full external domain of CD1a
- CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin
- CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells
- CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X
- CD1a is expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues
- CD1a is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin
- The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells
- The human genome contains five CD1 family genes organized in a cluster on chromosome 1
- The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands
- CD1a localizes to the plasma membrane and recycles vesicles of the early endocytic system
- At least five CD1 genes (CD1a, b, c, d, and e) are identified
- Alternatively spliced transcript variants of CD1a have been observed, but their biological validity have not been determined.