PIMA514756

Bcl-10 Monoclonal Antibody (4F8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514756-Each-of-1 In Stock ₹ 50,151.50

PIMA514756 - Each of 1

₹ 50,151.50

In Stock

Quantity

1

Base Price: ₹ 50,151.50

GST (18%): ₹ 9,027.27

Total Price: ₹ 59,178.77

Antigen

Bcl-10

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.03% sodium azide

Gene Accession No.

O95999, Q9Z0H7

Gene Symbols

BCL10

Immunogen

Purified recombinant fragment of human BCL-10 expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

4F8

Conjugate

Unconjugated

Gene

BCL10

Gene Alias

AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12042, 8915

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-14756 targets BCL-10 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and mouse samples
  • The MA5-14756 immunogen is purified recombinant fragment of human BCL-10 expressed in E
  • Coli
  • MA5-14756 detects BCL-10 which has a predicted molecular weight of approximately 26kDa
  • BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response
  • It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK
  • BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex
  • It is a substrate for MALT1
  • Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.