PIMA514878

Bcl-10 Monoclonal Antibody (E.177.7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514878-Each-of-1 In Stock ₹ 41,385.00

PIMA514878 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

Bcl-10

Classification

Monoclonal

Concentration

32 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

O95999, Q9QYN5, Q9Z0H7

Gene Symbols

BCL10

Immunogen

Synthetic peptide corresponding to residues surrounding Ser60 of Bcl10

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunoprecipitation, Western Blot

Clone

E.177.7

Conjugate

Unconjugated

Gene

BCL10

Gene Alias

AI132454; B cell CLL/lymphoma 10; B cell leukemia/lymphoma 10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; Bcl-10; BCL10 immune signaling adaptor; C81403; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; CARMEN; caspase-recruiting domain-containing protein; cCARMEN; cE10; c-E10; CED-3/ICH-1 prodomain homologous E10-like regulator; cellular homolog of vCARMEN; Cellular-E10; CIPER; Clap; hCLAP; IMD37; Mamm; mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; RCD; RP11-234D19.2; R-RCD1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12042, 83477, 8915

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response
  • It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK
  • BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex
  • It is a substrate for MALT1
  • Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.