SETD8 Monoclonal Antibody (B.540.4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514804-Each-of-1 | In Stock | ₹ 47,036.50 |
PIMA514804 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
SETD8
Classification
Monoclonal
Concentration
25 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
Q2YDW7, Q9NQR1
Gene Symbols
KMT5A
Immunogen
Synthetic peptide corresponding to human SET8 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
B.540.4
Conjugate
Unconjugated
Gene
KMT5A
Gene Alias
2410195B05Rik; AA617402; AW536475; H4-K20-HMTase; H4-K20-HMTase KMT5A; H4-K20-HMTase SETD8; H4-K20-specific histone methyltransferase; H4K20-specific histone methyltransferase splice variant Set8b; histone methyltransferase Pr-set7/Set8; histone-lysine N-methyltransferase KMT5A; histone-lysine N-methyltransferase SETD8; KMT5A; lysine (K)-specific methyltransferase 5A; lysine methyltransferase 5A; lysine N-methyltransferase 5A; Lysine-specific methylase 5A; N-lysine methyltransferase KMT5A; N-lysine methyltransferase SETD8; PR/SET domain containing protein 8; PR/SET domain-containing protein 07; PR/SET07; PRSET7; PR-Set7; RGD1305893; SET domain containing (lysine methyltransferase) 8; SET domain containing protein 8 variant 1; SET domain containing protein 8 variant 2; SET domain-containing 8; SET domain-containing protein 8; SET07; SET8; SETD8; Unknown (protein for MGC:134426)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
387893, 67956, 689820
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4
- H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression
- The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes
- It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis
- It is also involved in chromosome condensation and proper cytokinesis
- Nucleosomes are preferred as substrate compared to free histones.