NUMB Monoclonal Antibody (S.925.4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514897-Each-of-1 | In Stock | ₹ 52,955.00 |
PIMA514897 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,955.00
GST (18%): ₹ 9,531.90
Total Price: ₹ 62,486.90
Antigen
NUMB
Classification
Monoclonal
Concentration
88 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P49757
Gene Symbols
Numb
Immunogen
Synthetic peptide corresponding to residues surrounding Phe482 of human Numb protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
S.925.4
Conjugate
Unconjugated
Gene
Numb
Gene Alias
c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8650
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells
- Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex
- NUMB is also expressed in postmitotic neurons and plays a role in axonal growth
- Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.