PIMA514904

Phospho-Aurora A (Thr288) Monoclonal Antibody (F.131.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514904-Each-of-1 In Stock ₹ 52,955.00

PIMA514904 - Each of 1

₹ 52,955.00

In Stock

Quantity

1

Base Price: ₹ 52,955.00

GST (18%): ₹ 9,531.90

Total Price: ₹ 62,486.90

Antigen

Phospho-Aurora A (Thr288)

Classification

Monoclonal

Concentration

334 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

O14965

Gene Symbols

AURKA

Immunogen

Synthetic phosphopeptide corresponding to residues around pThr288 of human Aurora A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

F.131.2

Conjugate

Unconjugated

Gene

AURKA

Gene Alias

Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; Breast tumor-amplified kinase; BTAK; EC 2.7.11.1; hARK1; IAK; IAK1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; sereine threonine kinase; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; serine/threonine-protein kinase 6; aurora kinase A; serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; STK15; STK6; STK7; Unknown (protein for MGC:134472)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6790

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes
  • Overexpression of AURKA is observed in many types of cancer
  • Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation
  • Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal
  • Aurora A is viewed as a potential target for anticancer drug treatment
  • Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.