PIMA515000

B-Raf Monoclonal Antibody (H.600.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515000-Each-of-1 In Stock ₹ 41,385.00

PIMA515000 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

B-Raf

Classification

Monoclonal

Conjugate

Unconjugated

Gene

BRAF

Gene Alias

94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

109880, 114486, 673

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Clone

H.600.2

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P15056, P28028

Gene Symbols

BRAF

Immunogen

Synthetic peptide corresponding to human B-Raf

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus
  • It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron
  • This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
  • Mutations in B-Raf have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung
  • A pseudogene, which is located on chromosome X, has been identified for B-Raf.