Torc1 Monoclonal Antibody (T.292.2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514913-Each-of-1 | In Stock | ₹ 41,385.00 |
PIMA514913 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
Torc1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CRTC1
Gene Alias
AI413414; CH211-255D18.10; CH211-255D18.9; CREB regulated transcription coactivator 1; CREB regulated transcription coactivator 1b; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1b; CRTC1; crtc1b; FLJ14027; KIAA0616; MECT 1; Mect1; mKIAA0616; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1; Mucoepidermoid carcinoma translocated protein 1 homolog; R74955; si:ch211-255d18.8; TORC1; TORC-1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; transducer of regulated cAMP response element-binding protein 1; WAMTP1; zfTorc1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23373, 382056, 684527
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Clone
T.292.2
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
Q157S1, Q68ED7, Q6UUV9
Gene Symbols
CRTC1
Immunogen
Synthetic peptide corresponding to residues surrounding Val463 of human TORC1 (CRTC1) protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- It is not recommended to aliquot this antibody
- Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites
- Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation
- Enhances the interaction of CREB1 with TAF4
- Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR
- Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells
- In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses
- May be required for dendritic growth of developing cortical neurons
- In concert with SIK1, regulates the light-induced entrainment of the circadian clock
- In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock
- [UniProt]