PIMA515666

Torc1 Monoclonal Antibody (1B5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515666-Each-of-1 In Stock ₹ 50,062.50

PIMA515666 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

Torc1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q6UUV9

Gene Symbols

CRTC1

Immunogen

Purified recombinant fragment of human CRTC1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

23373

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone

1B5

Conjugate

Unconjugated

Gene

CRTC1

Gene Alias

AI413414; CH211-255D18.10; CH211-255D18.9; CREB regulated transcription coactivator 1; CREB regulated transcription coactivator 1b; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CREB-regulated transcription coactivator 1b; CRTC1; crtc1b; FLJ14027; KIAA0616; MECT 1; Mect1; mKIAA0616; mucoepidermoid carcinoma translocated 1; mucoepidermoid carcinoma translocated protein 1; Mucoepidermoid carcinoma translocated protein 1 homolog; R74955; si:ch211-255d18.8; TORC1; TORC-1; transducer of CREB protein 1; transducer of regulated cAMP response element-binding protein (CREB) 1; transducer of regulated cAMP response element-binding protein 1; WAMTP1; zfTorc1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15666 targets CRTC1 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples
  • The MA5-15666 immunogen is purified recombinant fragment of human CRTC1 expressed in E
  • Coli
  • MA5-15666 detects CRTC1 which has a predicted molecular weight of approximately 67kDa
  • Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites
  • Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation
  • Enhances the interaction of CREB1 with TAF4
  • Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR
  • Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells
  • In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses
  • May be required for dendritic growth of developing cortical neurons
  • In concert with SIK1, regulates the light-induced entrainment of the circadian clock
  • In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock
  • [UniProt]