ATGL Monoclonal Antibody (K.751.7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514990-Each-of-1 | In Stock | ₹ 53,489.00 |
PIMA514990 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,489.00
GST (18%): ₹ 9,628.02
Total Price: ₹ 63,117.02
Antigen
ATGL
Classification
Monoclonal
Concentration
23 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P0C548, Q8BJ56
Gene Symbols
PNPLA2
Immunogen
Synthetic peptide corresponding to residues surrounding Pro469 of mouse ATGL
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
K.751.7
Conjugate
Unconjugated
Gene
PNPLA2
Gene Alias
0610039C21Rik; 1110001C14Rik; adipose triglyceride lipase; ATGL; ATGL DESNUTRIN; calcium-independent phospholipase A2; Desnutrin; DKFZp667M109; FP17548; IPLA2 zeta; iPLA2zeta; IPLA2-zeta; mutant patatin-like phospholipase domain containing 2; patatin like phospholipase domain containing 2; patatin-like phospholipase domain containing 2; patatin-like phospholipase domain containing protein 2; patatin-like phospholipase domain-containing protein 2; PEDF R; PEDF-R; pigment epithelium-derived factor; plpl; plpl2; Pnpla2; RGD1309044; transport-secretion protein; Transport-secretion protein 2; transport-secretion protein 2.2; triglyceride hydrolase; TTS 2.2; TTS2; TTS2.2; TTS-2.2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
361676, 66853
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- Lipolytic enzymes are required for mobilization of fatty acids from triglyceride stores in adipose tissue
- Energy homeostasis is affected by dysfunctional lipolysis and may contribute to the pathogenesis of obesity and insulin resistance
- Until recently, hormone-sensitive lipase (HSL) was the only enzyme known to hydrolyze triglycerides in mammalian adipose tissue
- It is now thought that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis
- ATGL is highly expressed in adipose tissue of mice and humans
- It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets
- Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity
- Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals.