CDK9 Monoclonal Antibody (K.513.1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514912-Each-of-1 | In Stock | ₹ 47,125.50 |
PIMA514912 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,125.50
GST (18%): ₹ 8,482.59
Total Price: ₹ 55,608.09
Antigen
CDK9
Classification
Monoclonal
Concentration
163 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P50750, Q5EAB2, Q641Z4, Q99J95
Gene Symbols
CDK9
Immunogen
Synthetic peptide corresponding to residues near the carboxy terminus of human CDK9
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Canine, Hamster, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
K.513.1
Conjugate
Unconjugated
Gene
CDK9
Gene Alias
C-2k; CDC2L4; CDC2-related kinase; Cdk9; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; CTK1; cyclin dependent kinase 9; cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PITALRE; RP11-228B15.5; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK; Tat-associated kinase complex catalytic subunit
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100757719, 100855805, 1025, 107951, 362110, 520580
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- CDK9 is a serine/threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex
- This complex plays a key role in regulating the eukaryotic cell cycle
- CDK9 is coexpressed and copurified with CyclinT1
- CDK9 regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors
- CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis
- The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro
- Chronic activation of CDK9 causes cardiac myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.