GBL Monoclonal Antibody (E.169.2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514993-Each-of-1 | In Stock | ₹ 52,376.50 |
PIMA514993 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,376.50
GST (18%): ₹ 9,427.77
Total Price: ₹ 61,804.27
Antigen
GBL
Classification
Monoclonal
Concentration
69 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
Q9BVC4, Q9DCJ1, Q9Z2K5
Gene Symbols
MLST8
Immunogen
Synthetic peptide corresponding to residues surrounding Gln210 of human GβL
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
E.169.2
Conjugate
Unconjugated
Gene
MLST8
Gene Alias
0610033N12Rik; AA409454; AI505104; AI851821; G beta-like protein; G protein beta subunit-like; Gable; GbetaL; GBL; GBL protein; Lst8; Mammalian lethal with SEC13 protein 8; mLST8; mLST8 / mLST8; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); POP3; protein GbetaL; Target of rapamycin complex subunit LST8; TORC subunit gable; TORC subunit LST8; TORC subunit WAT1; transducin (beta)-like 4; WAT1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56716, 64223, 64226
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- G-protein beta subunit like (GBL protein) is a novel member of WD-40 protein family
- It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs
- LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway
- It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor
- LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1
- Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis
- Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis.