PIMA515038

Phospho-Cofilin (Ser3) Monoclonal Antibody (G.577.4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515038-Each-of-1 In Stock ₹ 47,036.50

PIMA515038 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

Phospho-Cofilin (Ser3)

Classification

Monoclonal

Concentration

21 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P18760, P23528, P45592, Q5E9F7

Gene Symbols

CFL1

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pSer3 of human cofilin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

G.577.4

Conjugate

Unconjugated

Gene

CFL1

Gene Alias

18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1072, 12631, 29271, 534553

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity
  • Regulates actin cytoskeleton dynamics
  • Important for normal progress through mitosis and normal cytokinesis
  • Plays a role in the regulation of cell morphology and cytoskeletal organization
  • Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation
  • Required for neural tube morphogenesis and neural crest cell migration.