PIMA515107

CD56 Monoclonal Antibody (G.611.8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515107-Each-of-1 In Stock ₹ 52,376.50

PIMA515107 - Each of 1

₹ 52,376.50

In Stock

Quantity

1

Base Price: ₹ 52,376.50

GST (18%): ₹ 9,427.77

Total Price: ₹ 61,804.27

Antigen

CD56

Classification

Monoclonal

Conjugate

Unconjugated

Gene

Ncam1

Gene Alias

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4684

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

G.611.8

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P13591

Gene Symbols

Ncam1

Immunogen

Membrane preparation of a small cell lung carcinoma specimen

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • It is not recommended to aliquot this antibody
  • CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa
  • CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity
  • Polysialic modification results in reduction of CD56-mediated cell adhesion
  • Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins
  • CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma
  • Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors
  • Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.