Dynamin 1 Monoclonal Antibody (3G4B6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515285-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA515285 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
Dynamin 1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P21575, P39053, Q05193
Gene Symbols
DNM1
Immunogen
Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
13429, 140694, 1759
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
3G4B6
Conjugate
Unconjugated
Gene
DNM1
Gene Alias
AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- MA5-15285 targets Dynamin-1 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15285 immunogen is purified recombinant fragment of human Dynamin-1 expressed in E
- Coli
- MA5-15285 detects Dynamin-1 which has a predicted molecular weight of approximately 97kDa
- Dynamin is a GTPase required for endocytosis of clathrin coated vesicles from the membrane
- Dynamin's involvement in endocytosis was first discovered during the characterization of the temperature sensitive parylytic shibire mutation from Drosophila melanogaster
- Three closely related isoforms have been identified in mammals
- Dynamin1 is expressed exclusively in neurons, dynamin2 is ubiquitously expressed and dynamin3 is expressed primarily in the testes
- Each of these isoforms of dynamin also has several splice variants
- This suggests that each isoform/splice variant may have separate intracellular targets or function in the budding of distinct vesicle types
- Common domain features of the dynamin proteins include an amino acid terminal GTPase domain, a central pleckstrin homology domain and a highly basic proline rich carboxyl terminus with several Src homology 3 (SH3) domains
- These SH3 domains target the dynamin to the clathrin coated pit
- Dynamin is known to interact with at least two proteins, AP2 adaptor protein complex and amphiphysin.