PIMA515408

PAR4 Monoclonal Antibody (3G9H7,4H12E9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515408-Each-of-1 In Stock ₹ 50,151.50

PIMA515408 - Each of 1

₹ 50,151.50

In Stock

Quantity

1

Base Price: ₹ 50,151.50

GST (18%): ₹ 9,027.27

Total Price: ₹ 59,178.77

Antigen

PAR4

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q96IZ0

Gene Symbols

Pawr

Immunogen

Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

5074

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

3G9H7,4H12E9, 4H12E9

Conjugate

Unconjugated

Gene

Pawr

Gene Alias

2310001G03Rik; coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; F2R like thrombin/trypsin receptor 3; F2RL3; PAR4; Par-4; par-4 induced by effectors of apoptosis; Pawr; PRKC apoptosis WT1 regulator protein; PRKC, apoptosis, WT1, regulator; pro-apoptotic WT1 regulator; prostate apoptosis response 4; prostate apoptosis response 4 protein; Prostate apoptosis response protein 4; prostate apoptosis response protein PAR-4; prostate apoptosis response-4; protease-activated receptor-4; proteinase-activated receptor 4; Thrombin receptor-like 3; transcriptional repressor PAR4; transcriptional repressor Par-4-like protein PAWR; WT1-interacting protein

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15408 targets PAR4 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
  • The MA5-15408 immunogen is purified recombinant fragment of PAR4(aa1-330) expressed in E
  • Coli.<br>
  • This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms
  • The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway
  • This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors
  • The encoded protein also plays an important role in the progression of age-related diseases.