PIMA515422

HGK Monoclonal Antibody (4H9E7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515422-Each-of-1 In Stock ₹ 50,062.50

PIMA515422 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

HGK

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

O95819

Gene Symbols

MAP4K4

Immunogen

Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

9448

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

4H9E7

Conjugate

Unconjugated

Gene

MAP4K4

Gene Alias

9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15422 targets MAP4K4 in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15422 immunogen is purified recombinant fragment of MAP4K4 (aa400-500) expressed in E
  • Coli
  • MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha
  • It appears to act upstream of the JUN N-terminal pathway
  • This protein is thought to interact with the SH3 domain of the adapter proteins Nck
  • HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A
  • Expression appears to be ubiquitous, expressed in all tissue types examined
  • Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.