PIMA515453

LIN28A Monoclonal Antibody (6D1F9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515453-Each-of-1 In Stock ₹ 62,122.00

PIMA515453 - Each of 1

₹ 62,122.00

In Stock

Quantity

1

Base Price: ₹ 62,122.00

GST (18%): ₹ 11,181.96

Total Price: ₹ 73,303.96

Antigen

LIN28A

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.03% sodium azide; pH 7.4

Gene Accession No.

Q9H9Z2

Gene Symbols

LIN28A

Immunogen

Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

6D1F9

Conjugate

Unconjugated

Gene

LIN28A

Gene Alias

AL024421; CSDD1; ENSMUSG00000070700; FLJ12457; Gm10299; Lin28; LIN-28; lin-28 homolog A; lin-28 homolog A (C. elegans); Lin28a; lin-28A; Protein lin-28 homolog A; RGD1566408; RNA-binding protein LIN-28; sb:cb650; si:ch211-232d9.4; similar to RNA-binding protein LIN-28; testis expressed gene 17; testis-expressed protein 17; Tex17; ZCCHC1; zgc:55584; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

79727

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-15453 targets LIN28 in indirect ELISA, IF, ICC, and WB applications and shows reactivity with human samples
  • The MA5-15453 immunogen is purified recombinant fragment of LIN28 (aa93-209) expressed in E
  • Coli
  • MA5-15453 detects LIN28 which has a predicted molecular weight of approximately 23kDa
  • Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C
  • elegans
  • The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases
  • Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts
  • More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.