PIMA515601

DKK3 Monoclonal Antibody (4G7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515601-Each-of-1 In Stock ₹ 50,151.50

PIMA515601 - Each of 1

₹ 50,151.50

In Stock

Quantity

1

Base Price: ₹ 50,151.50

GST (18%): ₹ 9,027.27

Total Price: ₹ 59,178.77

Antigen

DKK3

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q9UBP4

Gene Symbols

DKK3

Immunogen

Purified recombinant fragment of human DKK3 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

27122

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

4G7

Conjugate

Unconjugated

Gene

DKK3

Gene Alias

AW061014; C87148; Dickkopf; dickkopf 3; dickkopf 3 homolog; Dickkopf gene 3; dickkopf homolog 3; dickkopf homolog 3 (Xenopus laevis); dickkopf WNT signaling pathway inhibitor 3; Dickkopf3; dickkopf-3; Dickkopf-related protein 3; DKK 3; Dkk3; dkk-3; hDkk 3; hDkk-3; hhDkk3; mDkk-3; p29; regulated in glioma; Reic; RIG; RIG-like 5-6; RIG-like 7-1; UNQ258/PRO295; Xenopus

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15601 targets DKK3 in indirect ELISA, FACS and WB applications and shows reactivity with Human and Non-human primate samples
  • The MA5-15601 immunogen is purified recombinant fragment of human DKK3 expressed in E
  • Coli
  • MA5-15601 detects DKK3 which has a predicted molecular weight of approximately 38kDa
  • DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each
  • The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane
  • The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids
  • All DKKs have several potential sites for cleavage by furin-type proteases
  • Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord
  • In situ hybridization reveals highest expression in mouse brain, eye, and heart.