CSK Monoclonal Antibody (5F3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515707-Each-of-1 | In Stock | ₹ 52,554.50 |
PIMA515707 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,554.50
GST (18%): ₹ 9,459.81
Total Price: ₹ 62,014.31
Antigen
CSK
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P32577, P41240, P41241
Gene Symbols
CSK
Immunogen
Purified recombinant fragment of human CSK expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
12988, 1445, 315707
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone
5F3
Conjugate
Unconjugated
Gene
CSK
Gene Alias
AW212630; CSK; CSK, non-receptor tyrosine kinase; C-SRC kinase; c-src tyrosine kinase; C-terminal Src kinase; MGC117393; p50CSK; protein-tyrosine kinase (CSK); protein-tyrosine kinase CYL; Protein-tyrosine kinase MPK-2; Tyrosine-protein kinase CSK
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15707 targets CSK in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples
- The MA5-15707 immunogen is purified recombinant fragment of human CSK expressed in E
- Coli
- MA5-15707 detects CSK which has a predicted molecular weight of approximately 50kDa
- CSK is a tyrosine kinase that has been shown to downregulate the activity of SRC oncoprotein through phosphorylation of its carboxy terminus
- Since cell transformation by SRC is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene
- CSK plays an important role in the regulation of cell growth, differentiation, migration, and immune responses
- CSK phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1
- CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft-associated protein PAG (Csk-binding protein).