PIMA515822
HPV Type 16 E7 Monoclonal Antibody (6F3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515822-Each-of-1 | In Stock | ₹ 52,554.50 |
PIMA515822 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,554.50
GST (18%): ₹ 9,459.81
Total Price: ₹ 62,014.31
Antigen
HPV Type 16 E7
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Clone
6F3
Conjugate
Unconjugated
Gene Alias
HPV 16-E7; HPV16E7; human papillomavirus
Immunogen
Purified recombinant fragment of E7 expressed in E. Coli.
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15822 targets E7 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15822 immunogen is purified recombinant fragment of E7 expressed in E
- Coli
- MA5-15822 detects E7 which has a predicted molecular weight of approximately 21kDa
- The HPV E7 proteins are small (HPV16 E7 comprising 98 amino acids, 15kDa), zinc binding phosphoproteins which are localised in the nucleus
- They are structurally and functionally similar to the E1A protein of subgenus C adenoviruses
- The first 16 amino-terminal amino acids of HPV16 E7 contain a region homologous to a segment of the conserved region 1 (CR1) of the E1A protein of subgenus C adenoviruses
- The next domain, up to amino acid 37, is homologous to the entire region 2 (CR2) of E1A
- Genetic studies have established that these domains are required for cell transformation in vitro, suggesting similarities in the mechanism of transformation by these viruses
- The CR2 homology region contains the LXCXE motif (residues 22-26) involved in binding to the tumour suppressor protein pRb.