PIMA515828

CD1a Monoclonal Antibody (6H3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515828-Each-of-1 In Stock ₹ 48,549.50

PIMA515828 - Each of 1

₹ 48,549.50

In Stock

Quantity

1

Base Price: ₹ 48,549.50

GST (18%): ₹ 8,738.91

Total Price: ₹ 57,288.41

Antigen

CD1a

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P06126

Gene Symbols

CD1A

Immunogen

Purified recombinant fragment of human CD1A expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

909

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

6H3

Conjugate

Unconjugated

Gene

CD1A

Gene Alias

CD1; CD1 antigen; CD1.1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cd1a1; CD1A1 antigen; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15828 targets CD1A in indirect ELISA, FACS and WB applications and shows reactivity with Human samples
  • The MA5-15828 immunogen is purified recombinant fragment of human CD1A expressed in E
  • Coli
  • MA5-15828 detects CD1A which has a predicted molecular weight of approximately 37kDa
  • CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin
  • CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells
  • CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X
  • CD1a is expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues
  • CD1a is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin
  • The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells
  • The human genome contains five CD1 family genes organized in a cluster on chromosome 1
  • The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands
  • CD1a localizes to the plasma membrane and recycles vesicles of the early endocytic system
  • At least five CD1 genes (CD1a, b, c, d, and e) are identified
  • Alternatively spliced transcript variants of CD1a have been observed, but their biological validity have not been determined.