TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516210-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA516210 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
TLR4/MD-2 Complex
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.
Q9JHF9, Q9QUK6
Gene Symbols
Ly96, Tlr4
Immunogen
Ba/F3 cell line expressing mouse TLR4 and MD-2
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone
MTS510
Conjugate
Unconjugated
Gene
Tlr4
Gene Alias
ARMD10; CD284; Esop1; ESOP-1; hToll; lipopolysaccharide response; Lps; Ly87; Ly96; Ly-96; Lymphocyte antigen 96; Md2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; Toll-like receptor 4
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
17087, 21898
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Suggested positive control: Raw or thioglycolate-elicited mouse macrophage cells
- MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs)
- TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses
- TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS
- The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.