PSMA Recombinant Rabbit Monoclonal Antibody (SP29), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516395-Each-of-1 | In Stock | ₹ 63,190.00 |
PIMA516395 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 63,190.00
GST (18%): ₹ 11,374.20
Total Price: ₹ 74,564.20
Antigen
PSMA
Classification
Recombinant Monoclonal
Conjugate
Unconjugated
Gene
FOLH1
Gene Alias
Cell growth-inhibiting gene 27 protein; FGCP; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1; FOLH; Folh1; Folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; GIG27; glutamate carboxylase II; glutamate carboxypeptidase 2; Glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; mopsm; Naalad; NAALAD1; NAALAdase; NAALADase I; N-acetylated alpha-linked acidic dipeptidase; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; prostate specific membrane antigen; prostate specific membrane antigen variant F; prostate-specific membrane antigen; Prostate-specific membrane antigen homolog; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2346
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Clone
SP29
Formulation
PBS, TBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
Q04609
Gene Symbols
FOLH1
Immunogen
Synthetic peptide derived from C-terminus of human PSMA.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
- A suggested positive control is prostate carcinoma
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family
- The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney
- A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia
- Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity
- In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer
- This gene likely arose from a duplication event of a nearby chromosomal region
- Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.