PIMA516421
Nestin Monoclonal Antibody (SP103), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516421-Each-of-1 | In Stock | ₹ 59,274.00 |
PIMA516421 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,274.00
GST (18%): ₹ 10,669.32
Total Price: ₹ 69,943.32
Antigen
Nestin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P48681
Gene Symbols
Nes
Immunogen
Synthetic peptide corresponding to C-terminus of human nestin.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
SP103
Conjugate
Unconjugated
Gene
Nes
Gene Alias
AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
10763
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
- A suggested positive control is kidney tissue
- Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells
- Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells
- Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors
- Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells
- Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.